The 3 rd Asia Chapter of the International Society for Peritoneal Dialysis -
نویسنده
چکیده
Diabetes is commonly present in the patients with endstage renal disease (ESRD) requiring regular renal replacement therapy. In continuous ambulatory peritoneal dialysis (CAPD) patients, supraphysiological concentration of dextrose has been widely used as dialysate in the peritoneal dialysis (PD) fluid for the past two decades. Depending on the period of exposure and the strength of the dextrose solution used, 320-700 kCalories of additional energy daily intake may result from peritoneal dialysis. Not surprisingly, this has caused some concern, not least due to the direct glucose toxicity to the peritoneum membrane but also the possible adverse metabolic consequences, such as obesity, increased insulin resistance and dyslipidaemia. However, is this concern regarding metabolic effect as a result of dextrose dialysate justified?
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